Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | transDMproB |
| GeneSet | NCI_IL6-MEDIATED SIGNALING EVENTS |
| Enrichment Score (ES) | 0.69209236 |
| Normalized Enrichment Score (NES) | 1.5628144 |
| Nominal p-value | 0.010548524 |
| FDR q-value | 0.21416269 |
| FWER p-Value | 0.932 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | STAT1 | 3936 5524 | 190 | 6.574 | 0.0921 | Yes | ||
| 2 | GAB1 | 18828 | 276 | 5.806 | 0.1780 | Yes | ||
| 3 | VAV1 | 23173 | 347 | 5.300 | 0.2568 | Yes | ||
| 4 | MAPK14 | 23313 | 429 | 4.797 | 0.3271 | Yes | ||
| 5 | STAT3 | 5525 9906 | 569 | 4.247 | 0.3858 | Yes | ||
| 6 | MCL1 | 15502 | 689 | 3.730 | 0.4374 | Yes | ||
| 7 | JAK1 | 15827 | 996 | 2.955 | 0.4670 | Yes | ||
| 8 | PRKCD | 21897 | 1065 | 2.795 | 0.5069 | Yes | ||
| 9 | PIAS1 | 7126 | 1179 | 2.563 | 0.5407 | Yes | ||
| 10 | IRF1 | 1336 1258 1433 9182 | 1205 | 2.524 | 0.5787 | Yes | ||
| 11 | GRB2 | 20149 | 1534 | 1.943 | 0.5913 | Yes | ||
| 12 | JUN | 15832 | 1670 | 1.759 | 0.6114 | Yes | ||
| 13 | TYK2 | 12058 19215 | 1683 | 1.742 | 0.6379 | Yes | ||
| 14 | SOCS3 | 20131 | 1779 | 1.638 | 0.6583 | Yes | ||
| 15 | HSP90B1 | 19657 | 1958 | 1.452 | 0.6713 | Yes | ||
| 16 | RAC1 | 16302 | 2500 | 0.969 | 0.6573 | Yes | ||
| 17 | TNFSF11 | 21745 | 2661 | 0.819 | 0.6614 | Yes | ||
| 18 | IL6ST | 4920 | 2717 | 0.771 | 0.6705 | Yes | ||
| 19 | FOS | 21202 | 2723 | 0.766 | 0.6821 | Yes | ||
| 20 | LBP | 14760 | 2752 | 0.738 | 0.6921 | Yes | ||
| 21 | MYC | 22465 9435 | 3045 | 0.531 | 0.6846 | No | ||
| 22 | PIAS3 | 15491 672 1906 | 3768 | 0.238 | 0.6495 | No | ||
| 23 | HCK | 14787 | 4391 | 0.120 | 0.6179 | No | ||
| 24 | SOS1 | 5476 | 4708 | 0.086 | 0.6022 | No | ||
| 25 | GAB2 | 1821 18184 2025 | 4834 | 0.077 | 0.5966 | No | ||
| 26 | PIK3R1 | 3170 | 4927 | 0.072 | 0.5928 | No | ||
| 27 | MITF | 17349 | 5440 | 0.048 | 0.5660 | No | ||
| 28 | CEBPB | 8733 | 5620 | 0.042 | 0.5570 | No | ||
| 29 | CRP | 8793 | 7114 | 0.012 | 0.4768 | No | ||
| 30 | FGG | 1891 | 7531 | 0.006 | 0.4545 | No | ||
| 31 | PIK3CA | 9562 | 7760 | 0.003 | 0.4423 | No | ||
| 32 | A2M | 17298 | 9501 | -0.021 | 0.3489 | No | ||
| 33 | PTPN11 | 5326 16391 9660 | 9715 | -0.024 | 0.3378 | No | ||
| 34 | IL6 | 16895 | 10906 | -0.045 | 0.2745 | No | ||
| 35 | JAK2 | 23893 9197 3706 | 11817 | -0.066 | 0.2265 | No | ||
| 36 | AKT1 | 8568 | 13190 | -0.131 | 0.1547 | No | ||
| 37 | IL6R | 1862 4919 | 13589 | -0.164 | 0.1358 | No | ||
| 38 | TIMP1 | 24366 | 14066 | -0.214 | 0.1135 | No | ||
| 39 | MAPK11 | 2264 9618 22163 | 14126 | -0.222 | 0.1138 | No | ||
| 40 | MAP2K6 | 20614 1414 | 15424 | -0.607 | 0.0534 | No | ||
| 41 | MAP2K4 | 20405 | 15684 | -0.770 | 0.0514 | No | ||
| 42 | CEBPD | 22846 | 15685 | -0.771 | 0.0634 | No | ||
| 43 | JUNB | 9201 | 16588 | -1.542 | 0.0389 | No | ||
| 44 | LMO4 | 15151 | 18076 | -4.510 | 0.0291 | No |
